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Lique M Coolen

Associate Dean College Arts & Sciences

Professor Biological Sciences





Integrated Sciences Building

Room 251J

PhD and Postdoctoral Training

Ph.D. Neuroscience, University Nijmegen, The Netherlands

Postdoctoral Fellow, Yale University, University Maryland, Baltimore

A Bit About Me

I received my Ph.D. from the University of Nijmegen in the Netherlands in 1995 and have been on faculty at the University of Cincinnati, Western University (Canada), University of Michigan, and University of Mississippi Medical Center (UMMC). I have published over 130 papers describing my research on sexual behavior, motivation and reward, drug addition, neuroendocrine function, and spinal cord injury and am known for my expertise in a wide range of techniques, including neuropharmacology, molecular biology, chemogenetics, neuroanatomy, and behavioral techniques. Moreover, I utilize numerous animal models in my research, including rat, mouse, hamster, and sheep. My research has been continuously funded by NIH and other federal and non-federal funding agencies. In addition, during my time at the Western University , I was awarded a Canada Research Chair and successfully competed for funding from the Canadian Institutes of Health Research and Natural Science and Engineering Research Council of Canada. I have received numerous awards for my research and teaching, including the CJ Herrick award from the American Association of Anatomists, the Canada Research Chair in Neurobiology of Motivation and Reward, and the Norman Nelson award for Teaching Excellence at the University of Mississippi Medical Center.

I have a long and successful track record of mentoring graduate students (PhD, MD/PhD, and MSc students), postdoctoral fellows, junior faculty, and medical and undergraduate students as research mentor in my laboratory. I have a strong commitment to graduate and postdoctoral training in general and serve as Associate Dean of Graduate and Postdoctoral Studies in the College of Arts and Sciences, and have previously served as Associate Dean for Graduate and Postdoctoral Studies at UMMC, and as associate and interim neuroscience graduate program director. I also currently serve and have served on national committees for graduate and postdoctoral education and organize professional and career development programs, including courses and workshops for enhancement of rigor and reproducibility at Kent and for professional societies. Notably, I am co-leader of the Foundations for Rigorous Neuroscience program for the Society for Neuroscience.

Select Publications (2020 only)

For a full list of my publications, go to my PubMed Bibliography or Google Scholar

Lehman MN, Coolen LM, Goodman RL. Importance of neuroanatomical data from domestic animals to the development and testing of the KNDy hypothesis for GnRH pulse generation. Domest Anim Endocrinol. 2020 Oct;73:106441.

Gonzalez-Fernandez E, Staursky D, Lucas K, Nguyen BV, Li M, Liu Y, Washington C, Coolen LM, Fan F, Roman RJ. 20-HETE Enzymes and Receptors in the Neurovascular Unit: Implications in Cerebrovascular Disease. Front Neurol. 2020;11:983.


Kuiper LB, Lucas KA, Mai V, Coolen LM. Enhancement of Drug Seeking Following Drug Taking in a Sexual Context Requires Anterior Cingulate Cortex Activity in Male Rats. Front Behav Neurosci.2020;14:87.


Amodei R, Gribbin K, He W, Lindgren I, Corder KR, Jonker SS, Estill CT, Coolen LM, Lehman MN, Whitler W, Stormshak F, Roselli CE. Role for Kisspeptin and Neurokinin B in Regulation of Luteinizing Hormone and Testosterone Secretion in the Fetal

Sheep. Endocrinology. 2020 Apr 1;161(4).


McCosh RB, Lopez JA, Szeligo BM, Bedenbaugh MN, Hileman SM, Coolen LM, Lehman MN, Goodman RL. Evidence that Nitric Oxide Is Critical for LH Surge Generation in Female Sheep. Endocrinology. 2020 Mar 1;161(3).




Work Experience

January 2019 - Now

July 2012 - December 2018

December 2010 - June 2012

December 2005 - November 2010

September 2003 - November 2005

September 1998 - August 2003

Professor Biological Sciences, Associate Dean Research Development, Graduate and Postdoctoral Affairs, College of Arts & Sciences, Kent State University

Professor Physiology and Biophysics, Associate Dean Graduate and Postdoctoral Studies, Director Faculty Research Development, University Mississipi Medical Center

Professor Psychology, Professor Molecular & Integrative Physiology, Associate and Interim Director Graduate Program in Neuroscience, University of Michigan

Professor, Department of Physiology & Pharmacology and Department of Anatomy & Cell Biology, Schulich School of Medicine & Dentistry, University of Western Ontario. Canada Research Chair in Neurobiology of Motivation and Reward

Associate Professor, Department of Cell Biology, Neurobiology and Anatomy, University of Cincinnati College of Medicine

Assistant Professor, Department of Cell Biology, Neurobiology and Anatomy, University of Cincinnati College of Medicine


Senior Research Grant #546402 (PI)

Determining spinal alterations in sexual reflex control


DOD SCI150225 (PI)

Determining Sensory Plasticity and Developing Recovery for Sexual Dysfunction in Chronic Spinal Cord Injured Male Rats


NIH R01 HD082135

(Co-I; Lehman-Goodman MPI)

Role of NKB in the control of GnRH secretion by ovarian steroids

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