Research & Initiatives
Our laboratories explore a number of topics in reproductive neuroendocrinology, social and drug reward behavior, and spinal cord injury
Neuroendocrine control of fertility
PI: Lehman and Coolen
Our lab investigates the neuronal pathways that control reproductive endocrine function using the sheep as a model. In particular, we investigate the mechanisms by which distinct cell populations in the hypothalamus control pulsatile and surge secretion of gonadotropin releasing hormone.
Neuroendocrine etiology of infertility
We investigate how changes to cells in the brain that control fertility, termed KNDy neurons, lead to polycystic ovarian syndrome (PCOS), the most common cause of infertility in women worldwide. To achieve this, we use a murine model of PCOS combined with cutting-edge anatomical and functional tools that permit the analysis of brain circuitry.